About   Help   FAQ
Symbol
Name
ID
Tnf
tumor necrosis factor
MGI:104798
Phenotype annotations related to liver/biliary system
*Aspects of the system are reported to show a normal phenotype.
Darker colors indicate more annotations
Human Phenotypes
Elevated hepatic iron concentration
Abnormality of the hepatic vasculature
Hepatosplenomegaly
Hepatomegaly
Abnormality of the liver
Cirrhosis
Micronodular cirrhosis
Hepatic fibrosis
Hepatocellular necrosis
Hepatitis
Subacute progressive viral hepatitis
Cholelithiasis
Biliary cirrhosis
Cholestasis
Prolonged neonatal jaundice
Hepatocellular carcinoma
Disease(s) Associated with TNF
beta thalassemia
cystic fibrosis
Gaucher's disease
hemochromatosis
hepatocellular carcinoma
hypochromic microcytic anemia
leprosy
pre-eclampsia

Mouse Phenotypes
liver/biliary system phenotype
hepatic necrosis
enlarged liver
increased liver weight
decreased liver free fatty acids level
chronic liver inflammation
hepatic steatosis
abnormal liver physiology
Availability Mouse Genotype
Lta/Tnftm1Eug/Lta/Tnftm1Eug
Tnftm1Ljo/Tnftm1Ljo *
Tnftm1Sek/Tnftm1Sek
Tnftm2Jods/Tnftm2Jods
Tg(Tek-Tnf*)5382Mcla/0
Tnftm1.1Sned/Tnftm1.1Sned
Lyz2tm1(cre)Ifo/Lyz2+  (conditional)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support.
last database update
04/23/2024
MGI 6.23
The Jackson Laboratory