Symbol Name ID |
Tnf
tumor necrosis factor MGI:104798 |
* | Aspects of the system are reported to show a normal phenotype. |
Darker colors indicate more annotations |
Human Phenotypes | Elevated hepatic iron concentration |
Abnormality of the hepatic vasculature |
Hepatosplenomegaly |
Hepatomegaly |
Abnormality of the liver |
Cirrhosis |
Micronodular cirrhosis |
Hepatic fibrosis |
Hepatocellular necrosis |
Hepatitis |
Subacute progressive viral hepatitis |
Cholelithiasis |
Biliary cirrhosis |
Cholestasis |
Prolonged neonatal jaundice |
Hepatocellular carcinoma |
Disease(s) Associated with TNF | ||||||||||||||||
beta thalassemia | ||||||||||||||||
cystic fibrosis | ||||||||||||||||
Gaucher's disease | ||||||||||||||||
hemochromatosis | ||||||||||||||||
hepatocellular carcinoma | ||||||||||||||||
hypochromic microcytic anemia | ||||||||||||||||
leprosy | ||||||||||||||||
pre-eclampsia |
Mouse Phenotypes | liver/biliary system phenotype |
hepatic necrosis |
enlarged liver |
increased liver weight |
decreased liver free fatty acids level |
chronic liver inflammation |
hepatic steatosis |
abnormal liver physiology |
|
Availability | Mouse Genotype | ||||||||
Lta/Tnftm1Eug/Lta/Tnftm1Eug | |||||||||
Tnftm1Ljo/Tnftm1Ljo | * | ||||||||
Tnftm1Sek/Tnftm1Sek | |||||||||
Tnftm2Jods/Tnftm2Jods | |||||||||
Tg(Tek-Tnf*)5382Mcla/0 | |||||||||
Tnftm1.1Sned/Tnftm1.1Sned Lyz2tm1(cre)Ifo/Lyz2+ (conditional) |
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 04/23/2024 MGI 6.23 |
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